Bonova 150mg Tablet

Uses of Bonova 150mg Tablet

Used to treat postmenopausal osteoporosis and reduce the risk of fractures.

How does Bonova 150mg Tablet work?

Bonova 150mg Tablet works by reducing the amount of calcium lost from your bones. This prevents your bones from getting weaker and reduces your risk of bone breakage (fractures).

Side Effects of Bonova 150mg Tablet

Common adverse effects include dyspepsia, nausea, diarrhea, stomach discomfort, muscular pains, headaches, and dizziness.

Quick Suggestions:

• Your doctor has prescribed Ibandronic Acid to make your bones stronger and lower the risk of fractures.
• Take it in the morning at least 30 minutes before eating or drinking anything.
• Maintain an upright posture for 30 minutes after taking the medication so the medicine does not irritate your food pipe.
• Bonova 150mg Tablet may cause the amount of calcium in your blood to fall. Take calcium-rich food in your diet and have regular blood tests to monitor the level of calcium in your blood.
• It is important to look after your mouth and teeth while you are taking this medicine. Have regular dental check-ups and inform your dentist about taking Ibandronic Acid.

Osteoporosis

Osteoporosis is a common bone disease characterized by reduced bone density and increased bone fragility, leading to an increased risk of fractures. Here are some key points about osteoporosis:

Definition:

• Osteoporosis is a condition in which the density and quality of bone are reduced.

Causes:

• Aging is a primary risk factor for osteoporosis.
• Postmenopausal women are at higher risk due to a decrease in estrogen levels.
• Other risk factors include a family history of the disease, low body weight, and certain medications or medical conditions.

Symptoms:

• Osteoporosis is often called a "silent disease" because it progresses without symptoms until a fracture occurs.
• Fractures of the hip, spine, and wrist are common and can result from minor falls or even everyday activities.

Diagnosis:

• Bone density testing, typically using a dual-energy X-ray absorptiometry (DXA) scan, is the gold standard for diagnosing osteoporosis.
• The results are usually reported as a T-score, which compares a person's bone density to that of a healthy young adult.

Prevention and Treatment:

• Lifestyle changes, including a diet rich in calcium and vitamin D, regular weight-bearing exercise, and avoiding smoking and excessive alcohol consumption, can help prevent osteoporosis.
• Medications, such as bisphosphonates, hormone therapy, and other bone-building drugs, may be prescribed to treat or prevent osteoporosis.

Consequences:

• Osteoporosis-related fractures can lead to chronic pain, disability, and a reduced quality of life.
• Hip fractures, in particular, can be life-threatening, especially in older adults.

Management:

• Management of osteoporosis involves reducing fracture risk, managing pain, and maintaining bone health through medication, lifestyle modifications, and falls prevention.

It's essential for individuals, especially postmenopausal women and those with risk factors, to be proactive in assessing their bone health and taking steps to prevent or manage osteoporosis to maintain strong and healthy bones throughout life.

Pharmacology

• Prevents bone resorption and inhibits osteoclastic activity.
• Selectively affects bone tissue by binding to hydroxyapatite, the mineral matrix of bone.
• Results in a net gain in bone mass by reducing the rate of bone turnover in postmenopausal women.

Dosage & Administration of Bonova 150mg Tablet

• The recommended dose is one 150 mg film-coated tablet once a month.
• Take the tablet with a full glass of plain water while sitting or standing upright.
• Do not chew or suck the tablet, and do not lie down for 60 minutes after taking it.
• If a once-monthly dose is missed, take it the morning after it is remembered, unless the next scheduled dose is within 7 days.

Interaction

• Calcium supplements, antacids, and other oral medicines with multivalent cations may interfere with absorption and should be taken at least 60 minutes apart.
• No significant drug interactions are expected due to ibandronic acid's minimal plasma protein binding and renal excretion.

Contraindications

• Hypersensitivity to ibandronic acid or its excipients.
• Uncorrected hypocalcemia.
• Esophageal abnormalities that hinder esophageal emptying.
• Inability to sit or stand upright for at least 60 minutes.

Pregnancy & Lactation

• Not recommended during pregnancy or breastfeeding.
• No clinical data on the use of ibandronic acid in pregnant women.
• It interferes with breastfeeding.

Precautions & Warnings

• Adequately address hypocalcemia and other bone and mineral metabolic abnormalities before starting treatment.
• Use with caution in patients with active upper gastrointestinal problems.
• Patients should be monitored for signs or symptoms of an esophageal response.
• Osteonecrosis of the jaw (ONJ) has been reported in patients receiving bisphosphonates, especially cancer patients.

Storage Conditions

• Store below 30°C, away from light and moisture, and out of children's reach.